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Perkin synthesis : ウィキペディア英語版
Perkin reaction

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The Perkin reaction is an organic reaction developed by William Henry Perkin that is used to make cinnamic acids. It gives an α,β-unsaturated aromatic acid by the aldol condensation of an aromatic aldehyde and an acid anhydride, in the presence of an alkali salt of the acid. The alkali salt acts as a base catalyst, and other bases can be used instead.
Several reviews have been written.〔House, H. O. (1972) ''Modern Synthetic Reactions'', W. A. Benjamin, Menlo Park, California, 2nd ed, pp. 660–663〕
==Reaction mechanism==

The above mechanism is not universally accepted, as several other versions exist, including decarboxylation without acetic group transfer.〔Bansal, Raj K. (1998) ''Organic Reaction Mechanisms'', Tata McGraw Hill, 3rd Edition , pp. 199–201, ISBN 9780470858585 .〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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